In-Depth Articles on Resistance Physiology

Detailed explorations of mechanisms, research evidence, and physiological interactions between resistance training and energy restriction.

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Featured Articles

Each article below examines specific physiological aspects and integrates current research evidence. Explore topics ranging from cellular signalling mechanisms to longitudinal study outcomes.

Muscle Protein Synthesis Regulation During Energy Restriction

An exploration of anabolic signalling pathways, mTOR regulation, amino acid sensing, and protein turnover dynamics in hypocaloric conditions. Learn how the body balances protein breakdown and synthesis when energy is restricted.

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Mechanical Tension as a Stimulus in Energy Deficit

Analysis of how load application generates adaptive signals independent of energy status. This article focuses on tension magnitude, training variables, and the mechanisms by which mechanical stress stimulates muscle adaptation despite caloric restriction.

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Strength Adaptations in Hypocaloric States: Research Data

A summary of longitudinal research findings on strength changes, neural adaptation factors, and mechanical adaptations observed during energy restriction combined with resistance training. Includes interpretation of meta-analytic data.

Explore energy deficit research

Energy Expenditure Contribution from Resistance Training

Quantification of how resistance exercise affects total daily energy expenditure through acute exercise cost, excess post-exercise oxygen consumption (EPOC), and chronic resting energy expenditure (REE) elevation.

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AMPK-mTOR Crosstalk in Restricted Energy Availability

A mechanistic examination of metabolic sensing pathways, energy-dependent signalling switches, and how resistance training-induced signals override AMPK suppression to permit protein synthesis during energy deficit.

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Lean Mass Outcomes in Combined Diet and Resistance Studies

Meta-analytic review of clinical trial data examining lean mass preservation, body composition changes, and outcomes across varying deficit magnitudes, training intensities, and intervention durations.

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Important Limitations and Context

All articles on this resource present educational information and research summaries. Content is informational only and does not constitute personal recommendations or exercise guidance.

Individual responses to training and energy deficit vary based on genetics, training history, age, and other factors. Observations presented represent trends from population-level research and may not apply to specific individuals.